Faculty

 

Pharmacology

 

1. Head of Department: Prof. Arunabha Ray

 

Prof. Arunabha Ray is Head, Dept. of Pharmacology at Vallabhbhai Patel Chest Institute, Faculty of Medicine, University of Delhi.

 

Prof. Ray is a medical graduate (MBBS) from the University of Calcutta, with MD and PhD degrees in Pharmacology from the Faculty of Medicine, University of Delhi, and subsequently, he had postdoctoral training/experience in the USA and Canada.

 

He has more than 33 years of teaching and research experience in basic and clinical pharmacology at undergraduate and postgraduate levels, and is actively involved in the teaching and supervising biomedical research activities of postgraduate as well as doctoral students in pharmacology and toxicology of the University of Delhi. He is prolific researcher and is actively pursuing extramurally funded projects involving clinical and pre-clinical research using the innovative translational approach in the areas of his research interest.

 

He has been invited faculty to several international and national conferences and visiting scientist to several international universities/institutions to deliver talks in his area of expertise. He is member/expert of several technical/scientific advisory committees/boards in leading institutions and organizations in India and abroad. He has been the recipient of several awards, honors and fellowships from apex scientific and professional bodies for his contributions in the area of medical teaching and research. Most notably, he was elected as FAMS in 2005 for his contributions in his field.

 

He has more than 150 research publications which include papers in high impact factor national and international journals, invited reviews, monographs and articles in important conference proceedings. In addition, he has also authored one textbook in Pharmacology and edited four books in his areas of expertise.

 

 

Research areas:

In basic and clinical pharmacology and toxicology in the following areas:

                    1.      Respiratory Pharmacology & Toxicology
                 

                    2.       Immunopharmacology & Immunotoxicology

                    3.      Stress Pharmacology

                    3.      Nitric Oxide research

                    4.      Herbal Drug Research

                    6.       Translational Pharmacology

 

Ongoing and completed research projects

 

 

 

(a)  Pharmacological studies on the role of NO and NO meditaed signallineg pathways inacute and chronic hypoxia induced neurobehavioral and immunological changes in rats (DRDE funded, 7.0 lakhs, 2011-ongoing)

 

(b) Pharmacological studies on stress-induced inflammation and immunity : possible regulatory role for nitric oxide (NO) - (UGC funded, 10.5 lakhs, 2011 – ongoing)

(c) DST-FIST grant for development of Clinical Pharmacology Unit at the VPCI (35.0 lakhs, 2010-ongoing)

(d) Calcium phosphate nanoparticles co-encapsulating neurotherapeutic gene and drug for targeted therapy of neurodegenerative disorders – as part of the naomedicine initiative at the VPCI, in collaboration with Dept. of Chemistry, University of Delhi (DBT funded, 25.0 lakhs, 2011- ongoing).

(e) Preclinical toxicity evaluation of two polyherbal Unani formulations with therapeutic efficacy in sinusitis (CCRUM-AYUSH funded, 8.0 lakhs, 2011-ongoing)

(f) Brain nitric oxide and high altitude stress (DRDO funded – Jt. With Dept. of Physiology, 50.0 lakhs, 2009- ongoing)

(g) A randomized, double blind, placebo controlled, clinical study to evaluate the possible beneficial effects of UNIM-352, a polyherbal Unani formulation, in patients of bronchial asthma (Funded by CCRUM, New Delhi, completed)

(h) Studies on the possible mechanisms of action of UNIM-352 a ployherbal antiasthmatic preparation in experiment al animals (Funded by AYUSH, completed)

(i) A randomized, double blind, parallel design, placebo controlled, clinical trial to test the safety and efficacy of Livina, a polyherbal preparation, in anti-tubercular drug therapy induced hepatotoxicity in patients of pulmonary TB (Funded by Dey`s Medical Stores, Kolkata, completed)

(j) A Clinical Study to assess the safety and efficacy of LL-2123 HP, a polyherbal preparation, against ATT-induced liver damage (Funded by Lupin Limited, Mumbai, completed)

 

 

(k) Neuropeptidergic regulation of stress responses in experimental animals (Funded by UGC, Rs. 19000/-, completed)

 

(l)    Effects of stress on the HPA axis and gastric mucosal integrity in rats. (Funded by the ICMR, Rs. 4.5 lakhs, completed)

(m) Experimental studies on psychoneuroimmunological aspects of stress. (Funded by the UGC, Rs. 7.0 lakhs. cmpleted)

(n) Experimental Studies on the immunomodulatorry effects with 04 samples of Chywanprash(Funded by Dabur India Ltd., Rs. 1.60 lakhs, completd)

(o) A Clinical Study on the possible hepatoprotetive ...... Newlifit (a polyherbal preparation) ...... hepatitis ...... anti-tubercular thearpy (Funded by Dabur India Ltd., Rs. 6.50 lakhs, completed)

(p) Studies on the possible role of nitric oxide in the regulation of neurobehavioral and immunological responses to stress (Funded by DST, Rs. 17.00 lakhs, completed)

    

List of publications

 

 

 I. Papers published in indexed scientific journals.

 

 

 

1. Ray, A., Sharma, K.K., and Sen, P. Effect of histaminergic drugs on footshock-induced aggressive hehaviour in rats. European J. Pharmacol. 73 : 217-219, (1981).

2. Ray, A., Sharma, K.K. and Sen, P. Effect of morphine and naloxone in aggressive and non-aggressive mice: Role of opiate peptides. In Current Status of Centrally Acting Peptides. (Ed. B.N. Dhawan), Pergamon Press. London. Pp 127-132, (1982).

 

3. Ray, A., Sharma, K.K., Alkondon, M. and Sen, P. Modulation of footshock aggression in rats by clonidine: involvement of a1 and a2 adrenoceptors. J. Pharm Pharmacol. 35 : 595-596, (1983).


4. Ray, A., Sharma, K.K., Alkondon, M. and Sen, P. Possible interrelationship between the biogenic amines involved in the modulation of footshock aggression in rats. Arch Int. Pharmacodyn. Therap. 265 : 36-41, (1983).

 

5. Alkondon, M., Ray, A. and Sen, P.. Cholinesterase enzyme inhibition by some anti-arrhythmic drugs in vitro. Indian J. Pharmacol. 15 : 85-91, (1983).

 

6. Alkondon, M., Ray, A. and Sen, P. Effect of beta adrenergic blocking agents and some related drugs on plasma and RBC cholinesterase enzyme in vitro. Indian J. Exp, Biol. 21 : 519-521, (1983).

 

7. Ray, A., Alkondon, M. and Sen, P. Effect of propronolol on aggressive behaviour in rats. Indian J. Pharmacol. 16 : 129-131, (1984).

 

8. Alkondon, M., Ray, A. and Sen, P. Role of vagus in the antagonism of ouabain-induced arrhythmias in dogs by beta adrenergic blocking agents and related drugs. J. Pharm. Pharmacol. 36 : 702-704, (1984).

 

9. Alkondon, M., Ray, A. and Sen, P. Effect of some beta adrenergic blocking agents and related drugs on ciliary movement of frog oesophagus. Indian J. Exp. Biol. 22 : 382-385, (1984).

 

10. Alkondon, M., Ray, A. and Sen, P. Effects of beta adrenergic blocking agents with differing ancillary 8 properties on oxotremorine induced tremor in mice. Indian J. Exp. Biol. 22 : 382-383, (1984).

 

11. Ray, A., Alkondon, M. and Sen, P. The clinical significance of drug interactions. Ann. Nat. Acad. Med. Sci 20 : 142-158, (1984) (Review).

 

12. Alkondon, M., Ray, A. and Sen, P. Cholinergic involvement in the modulation of oxotremorine-tremor in mice by propranolol. Arch. Int. Pharmacodyn. Therap. 277 : 161-167, (1985).

 

13. Sen, P., Ray, A. and Alkondon, M. Two decades of beta adrenoceptor blockers in medicine. Indian J. Pharmacol. 17 : 127-131, (1985) (Review).

 

14. Ray, A. and Sen, P. Concepts in anti-platelet drug therapy. J. Anaes. Clin Pharmacol. 2 : 102-111. (1986) (Review).

 

15. Alkondon, M., Ray, A. and Sen. P. Autonomic regulation involved in the ocular hypotensive action of beta adrenergic blocking agents. J. Pharm. Pharmacol. 38 : 319-32, (1986).

 

16. Alkondon, M., Ray, A. Sen, P. An investigation into the mechanism of action of ocular hyptotensive effects of some beta adrenergic blockers. Symposium of Ocular Pharmacology (IUPHAR-Asian Congress of Pharmacology). pp. 61-64, (1985).

 

17. Alkondon, M., Ray, A. and Sen, P. Tissue cholinesterase inhibition by propranolol and related drugs. J. Pharm. Pharmacol. 8 : 168-42, (1986).

 

18. Alkondon, M., Ray, A. and Sen, P. Nonstereoselective aspects of propranolol pharmacodynamics. Canad. J. Physiol. Pharmacol. 64 : 1455-1462, (1986) (Review).

 

19. Ray, A., Alkondon, M. and Sen, P. Involvement of brain transmitters in the modulation of shock-induced aggression in rats by propranolol and related drugs. Pharmacol. Biochem. Behav. 26 : 229-234, (1987).

 

20. Khanna, N., Alkondon, M., Sen, P. and Ray, A., An investigation into the mechanisms involved in the modulation of acute inflammatory response in rats by propranolol. Indian J. Med. Res. 86 : 101-104, (1987).

 

21. Ray, A., Khanna, N., Bhattacharya, S.K. and Sen, P. Modulation of analgesic and anti-inflammatory effects of aspirin. Indian J. Med. Res. 86 : 264-268, (1987).

 

22. Ray, A., Henke, P.G. and Sullivan, R.M. The central amygdala and immobilization stress induced gastric pathology in rats : neurotensin and dopamine. Brain Res. 409 : 398-402, (1987).

 

23. Ray. A., Sullivan, R.M. and Henke, P.G. Adrenergic modulation of gastric stress pathology in rats : a cholinergic link. J. Autonom. Nerv. Syst., 20 : 265-268, (1987).

 

 24. Ray, A., Henke P.G. and Sullivan, R.M. Central dopamine systems and gastric stress pathology in rats. Physiol. Behav. 42 : 359-364, (1988).

 

25. Ray, A., Henke, P.G. Sullivan, R.M. Effects of intra-amygdalar dopamine agonists and antagonists on gastric stress ulcer formation in rats. Neurosic. Lett. 84 : 303-306, (1988).

 

26. Ray, A., Henke, P.G. and Sullivan, R.M. Opiate mechanisms in the central amygdala and gastric stress pathology in rats. Brain Res., 442 : 195-198. (1988).

 

27. Henke. P.G., Sullivan R.M. and Ray, A. Interactions of TRH with neurotensin and dopamine in the central amygdalar necleus during gastric stress ulcer formation. Neurosic. Lett. 91 : 95-100, (1988).

 

 28. Sullivan, R.M., Henke, P.G. and Ray, A. Effects of buspirone, a selective anxiolytic, on stress ulcer formation in rats. Pharmacol. Biochem. Behav. 31 : 317-319, (1988).

 

 29. Ray, A., Sen, P. and Alkondon, M. Biochemical and pharmacological evidence for a central cholinergic regulation of shock-induced aggression in rats. Pharmacol. Biochem. Behav. 32 : 867-871, (1989).

 

30. Khanna, N., Ray, A., Alkondon, M. and Sen, P. Effect of beta adrenoceptor antagonists and some related drugs on maximal electroshock seizures in mice. Indian J. Exp. Biol. 27 : 128-130, (1989).

 

31. Sullivan, R.M., Henke, P.G., Ray, A., Herbert, M.A. and Trimper, J.M. The GABA- benzodiazepine receptor complex in the central amygdalar necleus and stress ulcer in rats. Behav. Neural Biol. 51 : 262-269, (1989).

 

32. Ray, A., Henke, P.G. and Sullivan, R.M. Role of central amygdala in the dopaminergic modulation of gastric stress pathology in rats. Indian J. Med. Res. 90 : 224-228, (1989).

 

33. Ray, A. and Henke, P.G. Enkephalin-dopamine Interactions in the central amygdalar necleus during gastric stress ulcer formation in rats. Behav. Brain Res. 36 : 179-183, (1990).

 

34. Ray, A., Henke, P.G. and Sullivan, R.M. Noradrenergic mechanisms in the central amygdala and gastric stress pathology in rats. Neurosci. Lett. 110 : 331-336, (1990).

 

35. Ray, A., Henke P.G. and Sullivan, R.M. Effects of Intra-amygdalar thyrotropin releasing hormone and its antagonism by atropine and benzodiazepines during stress ulcer formation in rats. Pharmacol. Biochem. Behav. 36 : 597-601, (1990).

 

36. Ray, A., Khanna, N. and Sen, P. Possible prostaglandin-dopamine interactions during experinental gastric ulcer formation. Indian J. Exp. Biol. 28 : 562-565, (1990).

 

37. Ray, A., Mediratta, P.K., Puri, S. and Sen, P, Effects of stress on immune responsiveness, gastric ulcerogenesis and plasma corticosterone : modulation by diazepam and naltrexone. Indian J. Exp. Biol. 29 : 233-236, (1991).

 

38. Gulati, K., Ray, A. and Sharma, K.K. Role of diurnal variation and receptor specificity in the opioidergic regulation of food intake in free fed and food deprived rats. Physiol. Behav. 49 : 1065-1071, (1991).

 

39. Sen. P., Khanna, N.K. and Ray, A. Histaminergic mechanism in experimental convulsions, Indian J: Exp. Biol. 29 : 375-378, (1991).

 

40. Henke, P.G., Ray, A. and Sullivan, R.M. The amygdala, emotions and gut functions. Digest Dis. Sci. 36 (11) : 1633-1643, (1991).

 

41. Ray, A. and Henke, P.G. TRH-enkephalin interactions in the amygdalodoid complex during gastric stress ulcer formation in rats. Regul. Peptides. 35 : 11-17, (1991).

 

 42. Gulati, K., Ray, A. and Sharma, K.K. Effects of acute and chronic morphine on food intake : modulation by oxytocin and vasopressin. Pharmacol. Biochem. Behav. 40 : 27-32, (1991).

 

43. Puri, S., Ray, A., Chakravarti, A. and Sen, P. Role of histaminergic mechanisms in the regulations of stress responses in rats. Pharmacol. Biochem. Behav. 39 (4) : 847-850, (1991).

 

44. Ray, A. and Henke, P.G. The posterior basolateral amygdala, depamine and stress ulcer formation in rats. Brain Res., 558 : 335-338, (1991).

 

45. Gulati, K., Ray, A. and Sharma, K.K. Effects of acute and chronic ketocyclazocine and its modulation by oxytocin and vasopressin on food intake in rats. Pharmacol. Biochem. Behav. 41 : 7-12, (1991).

 

46. Sen, P. and Ray, A. Book Review on “Neural Development and Regeneration” (Springer -Verlag, New York), Indian J. Exp. Biol. 28 : 796-797, (1991).

 

47. Ray, A., Mediratta, P.K. and Sen, P. Modulation by naltrexone of stress induced changes in humoral immune responsiveness and gastric mucosal integrity in rats. Physiol. Behav. 51 : 293-296, (1992).

 

48. Henke, P.G. and Ray, A. The limbic brain, emotions and stress ulcers. Exp. Clin Gastroenterol. 1(4) : 287-291, (1992) (Review).

 

49. Sen, P., Maiti, P.C., Puri, S., Ray, A., Audulov, N.A. and Valdman, A.V. Mechanism of anti-stress activity of Ocimum Sanctum Linn, engenol and Tinospora malabarica in experimental animals. Indian J. Exp. Biol. 30 : 592-596, (1992).

 

50. Ray, A., Puri, S., Chakravarty, A.K. and Sen, P. Central histaminergic involvement during stress in rats. Indian J. Exp. Biol. 30 : 724-728, (1992).

 

51. Sen, P., Mendiratta, P.K. and Ray, A., Effects of Azadirachta indica A. juss on some biochemical, immunological and visceral parameters in normal and stressed rats. Indian J. Exp, Biol. 30 : 1170-1175, (1992).

 

52. Henke, P.G., Sullivan, R.M., Ray, A., and Mac Dougall, M.E. Stress ulcer modulation by chlordiazepoxide and GABA in the anterior cingulate cortex of rats. Exp. Clin. Gastroenterol. 2 : 13-15, (1992).

 

53. Henke, P.G. and Ray, A. Stress ulcer modulation by limbic system structures Acta Physiol. Hung. 80 : 117-125, (1992) (Review).

 

54. Ray, A., Gulati, K., Puri, S. and Sen, P. Role of Kappa opioid receptors and stress responsiveness in rats. Indian J. Exp. Biol. 31 : 116-119, (1993).

 

55. Ray, A., Gulati, K., Mediratta, P.K. and Sen, P. Opioidergic regulation of gastric ulcerogenesis and immune responses during stress in rats. Exp. Clin, Gastroenterol. 3 : 7-11, (1993).

 

56. Ray, A., Puri, S. and Sen, P. Brain histamine and stress ulcer formation in rats. Neurosci. Res. Comm. 13 : 37-43, (1993).

 

57. Ray, A., Henke, P.G., Gula ti, K. and Sen, P. The amygdalaloid complex, corticotropin releasing factor and stress ulcer formation in rats. Brain Res. 624 : 286-290.

 

58. Ray, A. Book Review on R-Ghosh’s Modern Concepts on Pharmacology and Therapeutics. (Hilton, Calcutta). Indian J. Exp. Biol. 31 : 581-582, (1993).

 

59. Ray, A. Book Review on “Neem-Research and Development” (Society of Pesticide Science, India, Div. of Agricultural Chemicals, AIRI, Govt. of India), J. Sci. Ind. Res. (1993).

 

60. Ray, A., Book Review on “Pharmacology” : Edited by M.M. Das, S.K. Maitra and others, (A Dutta and Mudrankan, Calcutta, 2nd Edition), Indian J. Pharmacol. 28 (1) : 90-91, (1994).

 

61. Puri, S., Sen, P., A.K. Chakravarti and Ray, A. A differential dipaminergic involvement during stress ulcero genesis in rats. Pharmacol. Biochem. Behav. 17 : 749-752, (1993).

 

62. Puri, S., Ray, A., A.K. Chakravarti and Sen, P. Role of dopaminergic mechanisms in the regulation of stress responses in rats. Pharmacol. Biochem. Behav. 48 : 53-56, (1994).

 

63. Lal, A., Seth, A. and Ray, A. Informing patients about drugs, Nat. Med. J. of India. 8 : 36-38, (1995).

 

64. Khanna, N., Goswami M., Sen, P. and Ray A., Modulation of pain sensitivity by Azadirachta indica (Neem) in mice. Indian J. Exp Biol. 33 : 848-850. (1995).

 

 65. Goswami, M., Mund, S. and Ray, A., Effects of some psychotropic agents on cognitive function in rats. Indian J. Physiol. Pharmacol. 40 (1) : 75-78, (1995).

 

66. Banerjee, B.D., Saha, S., Mahapatra, T.K. and Ray, A., Influence of dietary protein deficiency on DDT-indiced immune suppression in mice. Indian J. Exp. Biol. 33 (10) : 739-744, (1995).

 

 67. Lal, A., Moharana, A.K. Chandra, P. and Ray, A., Critical evaluation of refrences in drug advertisements : an Indian experience. J. Assoc. Phy. India. 44 : 778-779, (1996).

 

68. Banerjee, B.D., Ray, A. and Pasha S.T. Comparative evaluation of the immunotxicity of DDT and its metabolites in rats. Indian J. Exp. Biol. 34 : 517-552, (1996).

 

69. Ray, A., Banerjee, B.D. and Sen, P. Modulation of humoral and cell-mediated immune responses by Azadirachta Indica (Neem) in mice. Indian J. Exp. Biol. 34 : 698-701, (1996).

 

70. Banerjee, B.D., Koner, B.C., Ray, A. and Pasha, S.T. Influence of Subchronic exposure to lindane on humoral immunity in mice. Indian J. Exp. Biol. 34 : 1109-1113.

 

71. Banerjee, B.D., Koner, B.C. and Ray, A. Immunotoxicity of pesticides : Pespectives and trends. Indian J. Exp. Biol., 34 : 723-733, (1996) (Review).

 

72. Banerjee, B.D. Koner, B.C. and Ray, A. Influence of stress on DDT- induced modulation of the humoral immune responsiveness in mice. Environ. Res. 74 : 43-47, (1997).

 

 

 

73. Koner, B.C., Banerjee, B.D. and Ray, A. Stress - induced modulation of gammaglutamyl transpeptidase (GGT) activity in the lymphoid system: Modulation by drugs. Indian J. Exp. Biol. 35 : 222-224, (1997).


74. Koner, B.C., Banerjee, B.D. and
Ray, A., Modulation of GGT activity the lymphoid system by organochlorine insecticides in rats. Indian J. Exp. Biol., 35 : 1132-1134, (1997).

 

75. Banerjee, B.D., Pasha, S.T. Hussain, Q.Z. Koner, B.C., Ray, A.  A comparative evaluation of immunotoxicity of malathion after subchronic exposure in expeimental animals. Indian J. Exp. Biol 36:273-282 (1998).

 

76. Koner, B.C., Banerjee, B.D. and Ray, A., Effect of oxygen free radicals on immune responsiveness in rabbits : an in vivo study. Immunol. Lett. 59 : 127-131, (1997).

 

77. Koner, B.C., Banerjee, B.D. and Ray, A., Organochlorine induced oxidative stress and immune suppression in rats. Ind. J. Exp. Biol., 36 : 395 : 398, (1998).

 

78. Ray, A., and Anand, S. Recent trends in Anti fungal theropy focuss on Systemic Mycoses. Indian J. Chest. Dis. All. Sci 42 : 357-366 (2000).

 

78. Gulati K., Ray A., Debnath P.K. and Bhattacharya, S.K. Immunomodulatory Indian Medicinal Plants J. Nat. Remed. 2 : 121-131 (2002).

 

79. Masood, A, Banerjee, B.D. Vijayan, V.K. and Ray. A., Modulation of stress induced neurobehavioral changes by nitric oxide in rats. European J. Pharmacol . 458(2003) 135-139.

 

80. Ray. A., Masood, A., Gulati, K. and Banerjee B.D. Stress and Immunity. Mechamisms and Modulation by Drugs. In : Trends in Physiological Sciences Cells to System. (Ed : M Fahim); Shivam Press, New Delhi, 2002, pp. 406-423.

 

81. Masood, A, Banerjee, B.D. Vijayan, V.K. and Ray. A. Pharmacological and biochemical studies on the possible role of nitric oxide in stress adaptation in rats. European J. Pharmacol.  493 (2004), 111-115.

 

82. Gulati, K., Anand, S., Wardhan, N.,Vijayan, V.K., and Ray, A. Studies on the toxicodynamics of theophylline seizures : In search for an antidote. Clin Exp. Pharmacol. Physiol. 31 (2004) A187-A188.

 

 

83. Ray, A., Masood. A., Banerjee, B.D., Vijayan, V.K. Nitric oxide : A target molecule for drug development in stress and anxiety. Clin. Exp. Pharmacol. Physiol. 31 (2004) A 51.

 

 

84. Gulati, K. and Ray, A. Preventable adverse drug reactions : Focus on theophylline. In: Pharmacovigilance : An Update (Eds. A. Ray and K. Gulati), Image Graphics India, New Delhi, 2004, pp. 218-230.

 

85. Gulati, K., Anand S, Vijayan VK, Ray A. Stress-induced modulation of aminophylline seizures in rats : possible involvement of free radicals. Indian J Pharmacol. 36 (4) : 270-271, 2004.

 

86. Gulati K, Ray A, Vijayan VK. Possible role of free radicals in theophylline seizures in mice. Pharmacol. Biochem Behav. 82 : 241-245, 2005.

 

87. Ray A, Gulati K, Anand S, Vijayan VK. Pharmacological studies on the mechanisms in aminophylline induced seizures in rats. Indian J Exp. Biol. 43 : 849-853, 2005

 

88. Ray A, Gulati K. Nitric Oxide and the Central Nervous System : Perspectives and   Trends    In : Current Trends in Pharmacology (Eds: A Ray, K Gulati), IK International, New Delhi, 2006, pp. 367-381

 

89. Narayan P, Gulati K, Vijayan VK, Ray A. Experimental studies on the proconvulsant    effects of fluoroquinolones and its mechanisms. Indian J Pharmacol 37 : S 56, 2005

 

 

 

90. Anand R, Gulati K, Vijayan VK, Ray A. Experimental studies on the neurobehavioral       effects of theophylline. In : Proceedings of the 38th Annual IPS Conference, 2005, pp. 40-41.

 

91. Gulati K, Ray A, Vijayan VK. Free radicals and drug toxicity : Focus on theophylline. In : Current Trends in Pharmacology (Eds: A Ray, K Gulati), IK International, New Delhi, 2006, pp. 443-460.

 

92. Gulati K, Ray A, Studies on the mechanisms of anxiolytic and neuropeotective effects of melatonin in rats. Frontiers Neuroendocrinol. 27 : 129 -130, 2006.

 

93. Gulati K, Ray A, Masood A, Vijayan VK, Involvement of nitric oxide (NO) in the regulation of stress susceptibility and adaptation in rats. Indian J Exp Biol, 44:, 816-820, 2006

 

94. Pal R, Gulati K, Banerji BD, Ray A, Role of free radicals in stress-induced  neurobehavioral changes in rats. Indian J Exp Biol., 44 : 809-815, 2006.


 

96. Ray A. Modulation by thyrotropin releasing hormone (TRH) of stress responses in ratsFrontiers Neuroendocrinol 27 : 154 – 157, 2006.


97. Chakraborty A, Gulati K, Banerji BD, Ray A. Gender differences in stress susceptibility :     possible role of free radicals. Indian J Pharmacol. 38 : S 4, 2006

 

98. Vishnoi G, Gulati K, Vijayan VK, Ray A. Adverse drug reactions monitoring in outpatients of bronchial asthma. Indian J Pharmacol. 38 : S 25, 2006

 

99. Anand R, Gulati K, Vijayan VK, Ray A. Effects of morphine on stress-induced  neurobehavioral changes and its modulation by nitrergic agents in rats. Indian J Pharmacol.  38 : S 55, 2006

 

100. Chakraborty A, Gulati K, Banerji BD, Ray A. Possible involvement of freeradicals in the differential neurobehavioral responses to stress in male and female rats. Behave Brain Res. 179 : 321-325, 2007

 

101. Ray A, Chakraborti A, Gulati K. Current Trends in Nitric Oxide research. Cell Mol Biol 53 : 3-14, 2007.

 

102. Gulati K, Ray A. Free Radicals and Drug Toxicity : Focus on Theophylline, Cell. Mol. Biol. 53 : 42 – 52, 2007.

 

 

103. Gulati K, .Chakrabort A, Ray A. Modulation of stress induced neurobehavioral changes and brain oxidative injury by nitric oxide (NO) mimetics in rats. Behav Brain Res, 183: 226-230, 2007.

 

104. Chakraborti A, Gulati K, Ray A. Estrogen actions on brain and behavior : Recent insights and future challenges. Reviews in Neurosciences, 18: 395-416 2007.

 

105.  Gulati K, A Ray, Vijayan VK. Pharmacovigilance in special settings : A case study.  J   Pharmacovigilance & Drug Safety, 5: 32, 2007.

 

106.  Ray A, Gulati K, Tripathi SK. Good pharmacovigilance practices : A growing need. J Pharmacovigilance & Drug Safety, 5: 27, 2007.

 

107. Tyagi N, Gulati K, Vijayan VK, Ray A. A study to monitor adverse drug reactions in patients of chronic obstructive pulmonary disease : focus on theophylline. Indian J  Chest Dis All Sci 50 : 199- 202, 2008.

 

 

108. Chakraborti A, Gulati K, Ray A. Age related changes in stress-induced neurobehavioral  effects in rats modulation by antioxidants and nitrergic agents. Behav Brain Res 194   (1) : 86-91, 2008

 

109.  Gulati K, Chakraborti A, Banerji BD, Ray A. Experimental studies on the anti-oxidant role of nitric oxide during stress. Indian J Pharmacol 40 (Suppl.2): S130. 2008.

 

110.   Ray A, Gulati K, Tyagi N, Vishnoi G, Lal D, Vijyan VK. Pharmacovigilance in respiratory medicine: An experience with theophylline. Indian J Pharmacol 40  (Suppl.2): S206-207, 2008.

 

111. Gulati K, Chakraborti A, Ray A. Differential role of nitric oxide (NO) in acute and  chronic stress induced neurobehavioral modulation and oxidative injury in rats.  Pharmacol Biochem Behav, 92: 272-6, 2009

 

112. Gulati K, Ray A. Immunotoxicity In : Handbook of Toxicology of Chemical Warfare Agents ( ed. R Gupta ), Elsevier Publication, 595-60, 2009.


113. Ray A, Gulati K. Pharmacokinetics, In : Textbook of Pharmacology (3rd Edition), SD Seth and Vimlesh Seth (Eds.), Elsevier, NOIDA, India, 2009


 

114. Ray A, Gulati K. Pharmacodynamics, In : Textbook of Pharmacology (3rd   Edition), SD Seth and Vimlesh Seth (Eds.), Elsevier, NOIDA, India, 2009


 

115. Gulati K, Ray A and Vijayan VK. Role of oxidative and nitrosative stress during  theophylline induced seizures in experimental animals. J Cerebr Blood Flow Metab 29: S209–S212, 2009

 

116.   Ray A, Chakraborti A and Gulati K. Stress induced anxiogenesis and brain oxidative  injury in rats: Influence of age, sex and emotionality. J Cerebr Blood Flow Metab 29: S455–S466, 2009   

      

117. Gulati K, Ray A. Newer insights into the mechanisms of action of some herbal  adaptogens. In : Recent advances in herbal drug research and therapy, (Eds.  A Ray and K Gulati), IK International, New Delhi, 2009, pp. 201-218.


118. Pal R, Ahmed T, Kumar V, Suke SG, Ray A, Banerji BD. Protective effects of different Antioxidants against endosulfan induced oxidative stress and immunotoxicity in albino  rats. Indian J Exp Biol. 47 : 723 – 729, 2009.


119.  Gulati K, Ray A, Vijayan VK.Assessment of protective role of polyherbal preparation, Livina, against anti-tubercular drug induced liver dysfunction. Indian J Exp Biol., 48 :   318-322, 2010.


 

120. Gulati K, Banerji BD, Lall SB, Ray A. Effects of diesel exhaust, heavy metals and pesticideson various organ systems : possible mechanisms and strategies for prevention and treatment. Indian J Exp Biol. 48 : 710-721, 2010.


 

121. Gulati K, Ray A. Stress : its impact on developmental and reproductive toxicity. In : Handbook of developmental and reproductive toxicity (Ed. Ramesh Gupta), Elsevier, 2011, pp. 825-834.

 

 

122. Chakraborty A, Gulati K, Ray A. Involvement of nitric oxide in the protective effects of dehydroepiandrosterone sulphate on stress induced neurobehavioral suppression and brain oxidative injury in rats,. Europ J Pharmacol. 652 : 55-59, 2011.

 

123. Pal R, Gulati K, Banerji BD, Ray A. Possible involvement of free radicals in modulation of stress-induced immunological and biochemical changes in rats. Int. Immunopharmacol. 11 : 1680-1684, 2011.

 

 

124. Anand R, Gulati K , Ray A. Effects of morphine and its interactions with nitrergic agents during stress induced anxiogenesis in rats. Europ J Pharmacol, 2011 (comunicated)

 

125.  Gulati K, Chakraborti A, Ray A. Oestroge-nitric oxide interactions regulate gender based differences in stress susceptibility and adaptation in rats. J, Neurochem 2012 (comm.)

                                                

126. Chakraborty A, Gulati K, Ray A. Sex differences in stress induced anxiogenesis: possible       role of endogenous nitric oxide synthase inhibitor. Neurosci Lett 2012 (communicated)

 

127. Pal R, Gulati K, Banerji BD, Ray A. Pharmacological and biochemical studies on the protective effects of melatonin during stress-induced neurobehavioral and immunologic changes in relation to oxidative stress in rats. J Pineal Res 2012 (communicated)

 

 

II. Theses

 

 

 

1. Ray A. Role of biogenic amines in the aggressive behavior in experimental animals.M.D. (Pharmacology) thesis of the Faculty of Medicine, University of Delhi, 1981.

 

 

2. Ray A. Neuropeptidergic regulation of some psychoneuroimmunologica; aspects of stress. Ph.D thesis of the Faculty of Medicine, University of Delhi, 1993.

 

III. Textbook in pharmacology

 

 

 

Pharmacology by S.K. Bhattacharya, P. Sen and A. Ray (Ed : P.K. Das) 

 

(Pub: Elsevier Publications, New Delhi), 2003

 

IV.  Chapters in textbooks :

 

 

 

(a) In: Textbook of Pharmacology (National Book Trust, Govt. of India, Ed : Prof. S.D. Seth), 1999.

 

     

 

 

1. Introduction, Sources of Drugs                     :     A. Ray, A. Prakash, S.D. Seth

 

 

 

2. Pharmacodynamics                                       :     A. Ray

 

 

 

3. Pharmacokinetics                                          :     A. Ray

 

 

 

4. Gened-Based Therapy                                   :     A. Ray

 

 

 

5.  Alcohol                                                             :     K. Kishore, A. Ray

 

 

 

6. Anti-anxiety & Hypnotic drugs                         :     K. Kishore, A. Ray

 

 

 

7. Antiepiliptics                                                      :     K. Kishore, A. Ray, S.D. Seth

 

 

 

8. Drugs used in affective disorders.                   :     S.K. Bhattacharya, A. Ray

 

 

 

9. Antipsychotic drugs.                                          :     S.K. Bhattacharya, A. Ray

 

 

 

10. Opioid Analgesics and Antagonists               :     S.D. Seth, M.G. Moulik, A. Ray

 

 

 

11. Immunopharmacology                                    :     A. Ray

 

12. Nitric Oxide & Endothelins                              :     A. Ray

    

b) In : Textbook of Pharmacology (Eds. SD Seth and Vimlesh Seth); Elsevier, NOIDA, 2009)

   

 

1.    An Introduction to Pharmacology           :    SD Seth, A Ray

 

 

 

2.    Pharmacokinetics :                                  :   A Ray, K Gulati

 

 

 

3.    Pharmacodynamics:                                :   A Ray, K Gulati

 

 

 

4.    Gene Therapy:                                          :   A Ray, A Chakraborty

 

 

 

5.    Nitric Oxide and Endothelins:                  :   A Ray

 

 

 

6.    Basic aspects of Immunopharmacolog  :   A Ray

 

7.    Immunomodulators:                                   :   A Ray

 

V. Books edited

 

 

 

1. Pharmacovigilance : An Update

 

           (Eds: Arunabha Ray and Kavita Gulati, Image Graphics, Delhi, 2004)

 

 

 

2.  Current Trends in Pharmacology

 

             (Eds : Arunabha Ray and Kavita Gulati, IK International Pvt Ltd, New Delhi, 2007)

 

 

 

3.  Recent Advances in Herbal Drug Research and Therapy

 

(Eds. Arunabha Ray and Kavita Gulati, IK International, New Delhi, 2010)

 

 

 

4. Translational Research in New Drug Development

 

            (Eds. Arunabah Ray and Kavita Gulati, Neelam Graphics, Delhi, 2012 - in press)  

 

    

 

 

2. Dr Anita Kotwani, Associate Professor

 

Anita Kotwani joined VPCI as an associate professor in 2005. Prior to this appointment, she taught M.B.B.S. and B.D.S. students for over twenty years at Maulana Azad Medical College, New Delhi. Her areas of expertise include:

 

 

-          health policy;

 

 

-         surveillance of antimicrobial use in the community;

 

 

-         containment of antimicrobial resistance;

 

 

-         access to essential medicines;

 

 

-         rational use of medicines; and

-       treatment and quality of care of chronic diseases.

 

She is a pharmacologist with primary interests in how clinical and basic sciences are translated into clinical practice and health policy. In collaboration with WHO, Dr. Kotwani has developed a practical methodology that monitors antimicrobial use in the community, which is especially useful in resource-poor settings. She has also conducted qualitative studies of various stakeholders (such as physicians, chemists, and citizens) to ascertain antibiotic-use-related behaviour. The Government of India appointed Dr. Kotwani as a member of Ministry of Health task force, which is charged with assessing and proposing measures regarding antimicrobial use and resistance. Dr. Kotwani is member of National Working Group of the Global Antibiotic Resistance Partnership (GARP), India and work with them for containment of antimicrobial resistance. Additionally, Dr. Kotwani has expertise in measuring medicine prices, availability, affordability and price components in public and private sector. She has completed seven state-level surveys on medicine prices and availability; she also served as a technical advisor for several follow-up WHO/HAI studies on medicine prices in India. Dr. Kotwani also conducts research on quality of care for asthma patients. She studied baseline asthma management in New Delhi and conducted an intervention study as well as adherence and self-management patterns among patients. Her teaching responsibilities involve supervision of PhD and MD students engaged in basic and clinical research.

 

Selected Recent Achievements

-  Member on the Task Force Committee constituted by Health Secretary, Ministry of Health, Government of India, to formulate National Antibiotic Policy, 2010 -
 

- Technical Supervisor, WHO, medicine price and availability surveys, “Better Medicines for Children in India,” Orissa and Chhatisgarh, 2010.

- Member of the National Working Group of the Global Antibiotic Resistance Partnership (GARP)-India, 2009 -
                                                                          

- Established a methodology in collaboration with WHO for surveillance of antimicrobial use in the community in resource-constrained settings, 2003-2008

- Faculty, WHO Advanced Technical Briefing Seminar, Medicines Prices, Availability and Price Regulation, 2007 & 2008.

- Regional Technical Advisor (India), WHO-HAI Project on Medicine Prices, 2003-2008.
                                                                                                                       

- Visiting scholar, Department of Ambulatory Care and Prevention, Harvard Medical School, Boston, USA, May 2006.

 

Research Areas

 

The areas of research

 

-          Health policy;

 

-          Surveillance of antimicrobial use in the community;

 

-          Containment of antimicrobial resistance;

 

-          Access to essential medicines;

 

-          Rational use of medicines; and

-          Treatment and quality of care of chronic diseases

 

Ongoing and last ten years completed Research Projects (funded by external agencies)

 

· Measuring medicine prices and availability in National Capital Territory of Delhi – using WHO-HAI methodology. (Funded by WHO, SEARO) 2011-


. Study of Patterns of Antibiotic Dispensing in Pharmacies in Tumkur, Karnataka, India. (Resources for Future, Washington DC, funded project) 2010- 2011

 

. Regulation of pulmonary vascular tone during hypoxia induced pulmonary vasoconstriction. (LSRB, DRDO funded project) 2010

 

· Lipid reducing herbal compounds provides protection against diabetes induced cardiovascular disorders. (CCRUM, AYUSH funded project) 2010

 

· Surveillance of antimicrobial resistance and use in the community and in-depth qualitative investigation of various stakeholders for behaviour of antimicrobial drug use for suitable interventions for rational use of antibiotics. (Funded by WHO) 2009      

 

· Surveillance of use of antibiotics in diarrhoea and acute respiratory infection in the community. (Funded by WHO) 2009

 

· Medicine price components study in Delhi, India using WHO-HAI methodology. (Funded by DFID, London) 2007.

 

· Impact of Standard Treatment Guidelines and Patient Education on Quality of Asthma management. (Funded by HAI-AP) 2007.                                                                             

 

· Technical coordinator for WHO-HAI for six “Medicine Price” projects conducted in various states of India. (Funded by WHO-HAI) 2006.

 

· Field-testing a methodology to determine if the price a patient pays for a medicine differs from the price collected by a data collector in retail pharmacies. (Funded by WHO-HAI) 2005.

 

· Surveillance of antimicrobial resistance and use in the community – Phase 1. (Funded by WHO) 2004.                                                                                                     

 

· Prices and availability of medicines in Rajasthan, India using WHO-HAI manual on Medicine Prices. (Funded by WHO-HAI) 2003.

 

· Impact of educational intervention on prescribing behavior and cost of therapy in the treatment of bronchial asthma. (Funded by DSPRUD, India-WHO Essential Drugs Programme) 2002.

 

· Drug-use pattern and cost analysis in hypertension and bronchial asthma in colony and teaching hospital. (Funded by DSPRUD, India-WHO Essential Drugs Programme) 2001.

 

List of recent publications (last four years)

 

1. Kotwani A, Chhabra SK, Tayal V, Vijayan VK. Quality of asthma management in an urban community in Delhi, India. Indian Journal of Medical Research 2012; 135: 184-192. http://www.ijmr.org.in/temp/IndianJMedRes1352184-3630146_010030.pdf

2. Kotwani A, Chhabra SK. Impact of standard treatment guidelines and patient education on asthma control and knowledge in asthmatic patients: a controlled trial in Delhi, India. WHO South-East Asia Journal of Public Health 2012; 1: 42-51

3. Kotwani A, Roy Chaudhury R, Holloway K. Antibiotic prescribing practices of primary care prescribers for acute diarrhoea in New Delhi, India. Value in Health, 2012; 15: S116-S119.

 

4. Kotwani A. Report on: Medicine prices, availability, affordability, and medicine price components in NCT, Delhi: WHO/HAI methodology. December 2011. Available on www.haiweb.org

5. Rashid M, Fahim M, Kotwani A. Efficacy of tadalafil in chronic hypobaric hypoxia induced pulmonary hypertension:possible mechanisms. Fundamental and Clinical Pharmacology 2012, January 18, doi doi: 10.1111/j.1472-8206.2011.01013.x.

6. Rashid M, Kotwani A, Fahim M. Long-acting phosphodiesterase 5 inhibitor, tadalafil, and superoxide dismutase mimetic, tempol, protect against acute hypoxia-induced pulmonary hypertension in rats. Human and Experimental Toxicology 2011 online published December 5, 2011 doi: 10.1177/0960327111429138

7. Kotwani A. Transparency and accountability in public procurement of essential medicines in developing countries. International Journal of User-Driven Healthcare 2011; 1: 15-30.

8. Ganguly NK, Arora NK, Chandy SJ, Fairoze MN, Gill JS, Gupta U, Hossain S, Joglekar S, Joshi PC, Kakkar M, Kotwani A, Rattan A, Sudarshan H, Thomas K, Wattal C, Easton A, Laxminarayan R. Rationalizing antibiotic use to limit antibiotic resistance in India . Indian J Med Res 2011; 134:281-94.

9. Kotwani A, Wattal C, Katewa S, Joshi P C, Holloway K. Irrational use of antibiotics and role of pharmacists: an insight from a qualitative study in New Delhi, India. Journal of Clinical Pharmacy Therapeutics 2011 Online published 23 AUG 2011 DOI: 10.1111/j.1365-2710.2011.01293.x

10. Parveen A, Babbar R, Agarwal S, Kotwani A, Fahim M. Terminalia arjuna enhances baroreflex sensitivity and myocardial function in isoproterenol-induced chronic heart failure rats. Journal of Cardiovascular Pharmacology Therapeutics 2011 (August 9 2011 online publication) 1074248411416816

11. Kotwani A, Holloway K. Trends in antibiotic use among outpatients in New Delhi, India. BMC Infectious Diseases 2011;11:(20 April 2011)
http://www.biomedcentral.com/1471-2334/11/99

12. Singal G, Nanda A, Kotwani A. A comparative evaluation of price and quality of some branded versus branded-generic medicines of the same manufacturer in India. Indian Journal of Pharmacology 2011; 43: 131-136.

 

13. Holloway K, Mathai E, Gray A, on behalf of Community-based surveillance of antimicrobial use and resistance in resource-constrained settings Project Group (Kotwani A, et al). Surveillance of community antimicrobial resistance in resource-constrained settings – experience from five pilot projects. Tropical Medicine and International Health 2011; 16: 368-374.

 

14. Holloway K, Mathai E, Gray A, on behalf of Community-based surveillance of antimicrobial use and resistance in resource-constrained settings Project Group (Kotwani A, et al). Surveillance of community antimicrobial use in resource-constrained settings – experience from five pilot projects. Tropical Medicine and International Health 2011; 16: 152-161.

 

15. Singhal G.L., Kotwani A, Nanda A. Jan Audhadhi stores in India and quality of medicines therein.International Journal of Pharmacy and Pharmaceutical Sciences 2011; 3:204-207.

16. Parveen A, Babbar R, Agarwal S, Kotwani A, Fahim M. Mechanistic clues in the cardioprotective effect of Terminilia arjuna bark extract in isoproterenol-induced chronic heart failure in rats. Cardiovascular Toxicology 2011; 11; 48-57.

17. Kotwani A, Wattal C, Katewa S, Joshi P C, Holloway K. Antibiotic use in the community: what factors influence primary care physicians to prescribe antibiotics in Delhi, India? Family Practice 2010; 27: 684-690.

18. Kotwani A. Editorial. Access to essential medicines and standard treatment for chronic diseases. Indian Journal of Pharmacology 2010; 42: 127-128.

 

19. Kotwani A. Will generic drug stores improve access to essential medicines for the poor in India? Journal of Public Health Policy 2010; 31: 178-184.

20. Kotwani A, Holloway K, Roy Chaudhury R. Methodology for surveillance of antimicrobials use among out-patient in Delhi. Indian Journal of Medical Research 2009; 129: 555-60.

21. Wattal C, Raveendran R, Kotwani A, Sharma A, Bhandari SK, Sorensen TL, Holloway K. Establishing a new methodology for monitoring of antimicrobial resistance and use in the community in a resource poor-setting. Journal of Applied Therapeutic Research 2009; 7: 37-45.

 

22. WHO Research Series on Medicine (2009). Community-based surveillance of antimicrobial use and resistance in resource-constrained settings. Report on five pilot projects. Kotwani A (Antimicrobial drug use surveillance, Delhi site).World Health Organization, 2009 WHO/EMP/MAR/2009.2

 

23. Kotwani A. Availability, price, and affordability of asthma medicines in five Indian states. International Journal of Tuberculosis and Lung Diseases 2009; 13: 574-579.

 

24. Kotwani A, Gurbani N, Sharma S, Chaudhury R. Insights for policymakers from a medicine price survey in Rajasthan. Indian Journal of Medical Research 2009; 129: 451-454.

 

25. Kotwani A, Ewen M, Dey D et al. Correspondence – reply to Interaction between medical practitioners& pharmaceutical industry. Indian Journal of Medical Research 2008; 127: 94.

 

26. Kotwani A, Ewen M, Dey D et al. Medicine prices and availability at six sites in India: using the WHO-HAI methodology. Indian Journal of Medical Research 2007; 125: 645-54.

 

3. Kavita Gulati, Assistant Professor

 

Dr. Kavita Gulati is Associate Professor in Pharmacology at  Vallabhbhai Patel Chest Institute, University of Delhi. She obtained her masters degree in Pharmacology from the All India Institute of Medical Sciences and subsequently did her Ph.D from the University of Delhi. Dr Gulati has more than 22 years of teaching and research experience in Clinical and Experimental Pharmacology and Toxicology in different capacities in India and abroad. She is the recipient of several national awards including the Achari Prize and Uvnas Prize and the prestigious Prof. B.N. Ghosh Oration of the IPS. She is member of several professional bodies/societies relating to pharmacology and allied sciences (viz. National academy of Medical Sciences, International Neuroendocrine Federation, New York Academy of Sciences, Society of Toxicology, Society of Pharmacovigilance, Indian Pharmacological Society, etc. Her biography has also been include in the Marqui`s “Who is Who” in the world in science.  Her research interests are in Respiratory Pharmacology and Toxicology, Neuropharmacology and Stress Research, and she is the Principal Investigator of several extramurally funded research projects (viz. DST, AYUSH, CSIR, ICMR, etc.). She has the distinction of being invited to present talks at prestigious international meetings like IUPHAR (China), CMB Congress (France), World Stress Congress (Hungary), and CPT Congress (Australia). She has been visiting scientist to reputed international institutions like Semmelwies Medical University (Budapest, Hungary), University of Pittsburgh Medical Center (USA), Army Medical Institute (Xian, China), University of Minnesota at Minneapoilis (USA), University of Illinois at Chicago (USA), etc and expert member at different Institutions and Government organizations in her field. She has published extensively in leading national and international journals, is co-author of several chapters in reference and textbooks of Pharmacology, and co-editor of three books in Pharmacology.
 
Areas of Research :
 
(i)             Respiratory Pharmacology and Toxicology
(ii)           Neuropharmacology & Allied Neurosciences
(iii)         Stress Research
(iv)         Herbal drug research
 
O
 
ngoing and completed research projects:
a) P.I. in the DST funded research project entitled “Pharmacological studies on the role of nitric oxide (NO) in stress adaptation in rats” (Completed).
 
b) P.I. in ICMR funded research project entitled “Studies on the role of NO and NO-mediated signal transduction pathways during stress induced immunomodulation in rats”
 
c) P.I. in CSIR funded project entitled “Experimental studies on the possible role of nitric oxide (NO) during acute and chronic morphine effects in normal and stressed rats”
 
d) P.I. in AYUSH funded project entitled “Experimental studies on the cellular and   molecular mechanisms of action of UNIM-352, a polyherbal Unani preparation, to validate its use as a drug for bronchial asthma”

 
e) Co P.I. in AYUSH funded project entitled “Studies on the possible mechanisms involved in the effects of UNIM-352, a polyherbal, anti-asthmatic Unani preparation, in experimental animals” (completed).

f)Co P.I. in   CCRUM (AYUSH)  project entitled “Pre-clinical studies to evaluate the toxicity profile of (a) UNIM-051 and (b) UNIM-053, polyherbal Unani formulations with therapeutic potential in sinusitis”
 
g) Co P.I. in DRDE  (DRDO, Min. of Defence)  entitledPharmacological studies on the role of nitric oxide (NO) and NO-mediated signaling pathways in acute and chronic hypoxia induced behavioral and immunological changes in rats”
 
h) Co P.I. in DBT project entitled “Calcium phosphate nanoparticles co-encapsulating neuro therapeutic gene and drug for targeted therapy of neurodegenerative disorders”
 
 
 
 
List of Publication
In indexed Journals :
1) Kheterpal K. Lall SB, Rajdev S, Gupta YK. Effect of calcium channel blockers and saralasin on angiotensin II contractions in rabbit aortic strip. Indian J Physiol Pharmacol 30 : 166-170, 1986.
2) Lall SB, Kheterpal K, Rajdev S, Gupta YK. The effect of acute and chronic treatment of verapamil on pressor response to angiotensin II in rats. Indian J Physiol Pharmacol 30 : 145-148, 1986.
3) Arora RB, Kheterpal K, Khanna T, Khan SU, Khan EA. Efficacy of   standardized, safe, unani, coded drug Ajmaloon, a pharmaceutical preparation containing rauwolfia, Indian J Pharmacol 18: 29-41, 1986.
4) Arora RB, Hardard ME, Kheterpal K. Khanna T, Khan SU, Khan EA. Efficacy of a standardized, safe, unani, coded drug "Lipotab" in hypercholestremia and involvement of zinc in its mechanism. J Res Edu Indian Med 4: 49-56, 1986.
5) Kheterpal K, Khanna T, Arora RB, Siddiqui HH. Study of a Unani polypharmaceutical preparation, Joshina, as anti-tussive and expectorant in experimental model. Indian J Pharmacol. 19 : 200-204, 1987. 
6) Chandra D, Kheterpal K. Use of mating cages for food intake study in rats instead of metabolic cages. Indian J Pharmacol 20: 219-220, 1988.
7) Kheterpal K, Khanna T, Arora RB. In vitro and in vivo bronchorelaxant effect in guinea pigs of "Joshina", a herbal polypharmaceutical. J Ethnopharmacol 26: 183-187. 1989.
8) Arora RB, Kheterpal K, Khanna T, Khan SU. Possible interaction of some trace elements in mechanism of antihypertensive action of a polypharmaceutical, Ajmaloon. J Res Edu Indian Med 8: 17-21, 1989.
9) File SE, Zharkovsky A, Gulati K. Effects of baclofen and nitrendipine on ethanol withdrawal responses in the rats. Neuropharmacology 30: 183-190, 1991.
10) Gulati K, Ray A, Sharma KK. Role of diurnal variation and receptor specificity in the opioidergic regulation of food intake in free-fed and food-deprived rats. Physiol Behav 49: 1065-1071, 1991.
11) Gulati K, Ray A, Sharma KK. Effects of acute and chronic morphine on food- intake in rats: Modulation by oxytocin and vasopressin. Pharmacol Biochem Behav 40: 27-32, 1991.
12) Gulati K, Ray A, Sharma KK. Effect of acute and chronic ketocyclazocine and its modulation by oxytocin or vasopressin on food intake in rats. Pharmacol Biochem Behav 41: 7-12, 1991.
13) Gulati K, Ray A, Sharma KK. Effects of acute or chronic opioid agonist and their modulation by diurnal rhythmicity and satiety states on food intake in rats. Indian J Exp Biol 30: 185-189, 1992.
14) Gulati K, Sharma KK. Opioidergic regulation of food intake : Modulation by vasopressin. Indian J Pharmacol, 25: 18-23, 1993 (Awarded Achari Prize in 25th Annual conference of Indian Pharmacological Society, 1992).
15) Ray A, Gulati K, Puri S, Sen P. Role of kappa opioid receptors during stress responsiveness in rats. Indian J Exp Biol, 31: 116-119, 1993.
16) Ray A, Gulati K, Mediratta PK, Sen P. Opioidergic regulation of gastric ulcerogenesis and immune responsiveness during stress in rats. Exp Clin Gastroenterol, 3: 7-11, 1993.
17) Ray A, Henke PG, Gulati K, Sen P. The amygdaloid Complex, corticotropin releasing factor and stress induced gastric ulcerogenesis in rats. Brain Research, 624: 286-290, 1993.
18) Gulati K, Ray A, Effects of Intrahypothalamic morphine and its interaction with oxytocin and vassopressin during food intake in rats. Brain Research, 690, 99-103, 1995
19) Gulati K. Differential effects of intrahypothalamic administration of opioids on food intake in naive and tolerant rats. Pharmacol Biochem Behav. 52(4): 689-694, 1995
20) Gulati K, Sharma KK, Chandra D. Opioidergic regulation of food - intake. Ann Natl Acad Med Sci 29: 241-306, 1993.
21) Gulati K, Lall SB, Angiotensin-II receptor subtypes, characterization and pathophysiological implication. Indian J Exp Biol. 34: 91-97, 1996.
22) Lall SB, Dass N, Rama R, Peshin SS, Khatar S, Gulati K, Seth SD. Cadmium induced nephrotoxicity in rats. Indian J Exp Biol 35: 151-154, 1997.
23) Lall SB, Peshin SS, Gulati K, Khattar S, Das N, SEth SD. Involvement of renin-angiotensin system in the hypertensive effect of cadmium in rats. Indian J Exp Biol 35: 338-341, 1997.
24) Gulati K, Lall SB, Das BP, Seth SD. Effect of short and long term exposure to diesel exhaust on sensitivity of guinea pig tracheal preparation to histamine. Indian J Exp Biol 35: 837-40, 1997.
25) Lall SB, Das N., Das BP, Gulati K. Biochemical and histopathological changes in respiratory, system of rats following exposure to diesel exhaust. Indian J Exp Biol 36: 55-59, 1998.
26) Lall SB, Singh B, Gulati K, Seth SD. Role of nutrition in toxic injury. Indian J Exp Biol 37: 109-116, 1999.
27) Gulati K, Wardhan N, Anand S, Ray A. Studies on the toxicodynamics of aminophylline – induced seizures in mice. Indian J. Pharmacol. 35: 196-197, 2003.
28) Gulati K, Anand S, Vijayan VK and Ray A. Stress-induced modulation of aminophylline seizures in rats : Possible involvement of free radicals. Indian J Pharmacol. 36 : 270-271, 2004.
29) Gulati K, Ray A, Pal G, Vijayan VK. Possible role of free radicals in theophylline induced seizures in mice. Pharmacol. Biochem, Behav. 82 : 241-245, 2005
30) Ray A, Gulati K, Anand S, Vijayan VK. Pharmacological studies on the mechanisms of aminophylline induced seizures in rats. Indian J Exp Biol. 43: 849 – 853, 2005
31) Gulati K, Ray A. Studies on the mechanisms of anxiolytic and neuropeotective effects of melatonin in rats. Frontiers Neuroendocrinol. 27 : 129 -130, 2006.
32) Gulati K, Ray A, Masood A, Vijayan VK. Involvement of nitric oxide (NO) in   the regulation of stress susceptibility and adaptation in rats. Indian J Exp Biol, 44: 809-815, 2006.
33) Pal R, Gulati K, Banerji BD, Ray A. Role of free radicals in stress-induced neurobehavioral changes in rats. Indian J Exp Biol., 44: 816-820, 2006.
34) Ray A, Gulati K, Tyagi N, Vijayan VK. Adverse drug reactions : an overview. J Pharmacovigil Drug Safety 3 : 4 – 7, 2006.
35) Chakraborti A, Gulati K, Banerjee BD, Ray A. Possible involvement of free radicals in the differential neurobehavioral responses to stress in male and female rats. Behav Brain Res 179 : 321-325, 2007
36) Ray A, A.Chakraborti, Gulati K. Current trends in nitric oxide research. Cell Mol Biol, 53 :3-14, 2007
37) Gulati K, Ray A, Pal R. Free Radicals and Theophylline neurotoxicity :     An experimental study. Cell   Mol Biol, 53 : 42-52, 2007
38) Gulati K, .Chakrabort A, Ray A.  Modulation of stress induced neurobehavioral changes and brain oxidative injury by nitric oxide (NO) mimetics in rats. Behav Brain Res,183: 226-230, 2007.
39) Chakraborti A, Gulati K, Ray A. Estrogen actions on brain and behavior : Recent insights and future challenges. Reviews in Neurosciences, 18: 395-416 2007
40) Chakraborti A, Gulati K, Ray A. Age related changes in stress-induced neurobehavioral effects in rats modulation by antioxidants and nitrergic agents. Behav Brain Res194 (1) : 86-91, 2008
41) Gulati K, .Chakrabort A, Banerji BD, Ray A.  Experimental studies on the anti-oxidant role of nitric oxideduring stress. Indian J Pharmacol40 (Suppl.2): S130, 2008.
42).Tyagi N, Gulati K, Vijayan VK, Ray A. A study to monitor adverse drug reactions in patients of chronic obstructive pulmonary disease: focus on theophylline. Indian J Chest Dis All Sci 50 : 199-202, 2008
43).Gulati K, .Chakraborti A, Ray A. Differential role of nitric oxide (NO) in acute and chronic stress induced neurobehavioral modulation and oxidative injury in rats. Pharmacol Biochem Behav, 92: 272-6, 2009 (Awarded Uvnas prize of Indian pharmacology Society, 2010)
44).Gulati K, Ray A, Vijayan VK Assessment of protective role of polyherbal preparation, Livina against anti-tubercular drug induced liver dysfunction. Indian J Exp Biol. 48:318-322, 2010
45).Gulati K, Banerjee BD, Lall SB, Ray A. Effects of diesel exhaust, heavy metals and pesticides on various organ systems : Possible mechanisms and strategies for prevention and treatment. Indian J Exp Biol. 48:710-721, 2010
46).Gulati K, Chakraborty A, Ray A. Physiological and behavioral correlates of stress induced anxiogenesis in rats: possible role of free radicals. Indian J Pharmacol. 42 (Suppl.2), 128-129, 2011
47).Chakraborti A, Gulati K, Ray A. Involvement of nitric oxide in the protective effects of dehydroepiandrosterone sulphate on stress induced neurobehavioral suppression and brain oxidative injury in rats. Eur J Pharmacol, 652: 55-59, 2011.
48). Rishi Pal, Gulati K, Banerjee B, Ray A. Pharmacological and biochemical studies on the   role of free radicals during stress-induced immunomodulation in rats. International Immunopharmacology, 11:1680-1684, 2011
49). Pal R, Gulati K, Banerji BD, Ray A. Pharmacological and biochemical studies on the protective effects of melatonin during stress-induced neurobehavioral and immunological changes in relation to oxidative stress in rats. J Pineal Res, 2011 (communicated)
50) Anand R, Gulati K, and Ray. Pharmacological evidence for the role of nitric oxide (NO) in the modulation of stress induced anxiety by morphine in rats. Eur J Pharmacol. 2011(communicated).
51) Gulati K, Chakraborty A, Ray A Role of Oestrogen-nitric oxide (NO) interactions in the regulation of gender based differences in stress susceptibility and adaptation in rats. Physiol Behav. 2011(communicated).
 
 
 

Chapters in books

 
1). Arora RB, Subramaniam TAV, Bhatia B, Khan SU, Gaur SN, Kheterpal K. Khanna T. Role of zinc in health and disease. In 'Elements in Health and Disease' (Eds: Said M, Rahman MA & Silva LAD), Pakistan, Hamdard University Press, 1987
 
2). Arora RB, Hameed A, Subramaniam TAB, Roy S, Khan EA, Kheterpal K. Khan SU. Differential serum zinc concentration in some cardivascular diseases and broachial asthma. In "Metabolism of Minerals and Trace Elements in Human diseases" Eds: Abdulla M, Deshti H, Sarkar B, Sayer AH & Nageeb NA), New Delhi Smith-Gordon, 57-60, 1989.
         3). Kheterpal K, Khanna T, Imran M, Khan SU, Arora RB, Hammed A. Effect of "Lipotab" on experimentally induced cardiovascular pathology and its probable mechanism of action. In "Research and Development of Indigenous Drugs" (Eds Dandiya PC and Vohra SB, New Delhi, Interprint ,182-187, 1989.
4). Arora RB, Kheterpal K, Khanna T, Roy S, Khann SU. Role of electrolytes in development of druges for cardiac arrhythmias. In 'Calcium channel blockers and heart (Eds) Seth SD, Manchanda SC, Siddiqui HH. New Delhi, Interprint, 91-96, 1989.
5). Ray A, Masood A, Gulati K, Banerji BD. Stress and Immunity : Mechanisms and Modulations by Drugs . In : Trends in Physiological Sciences : From Cells to Systems (Ed : M. Fahim), New Delhi, Shivam Press, pp. 406 – 423, 2002.
 
6). Gulati K, Ray A . Preventable adverse drug reactions : focus on theophylline. In : Pharmacovigilance : An Update , Eds. A. Ray and K. Gulati , New Delhi Image Graphics India,   pp. 218 – 230, 2004.
7). Ray A, Gulati K. Nitric Oxide and the Central Nervous System : Perspectives and Trends. In : Current Trends in Pharmacology (Eds: A Ray, K Gulati), New Delhi IK International, pp.367-382, 2007.
8). Gulati K, Ray A, Vijayan VK. Free radicals and drug toxicity : Focus on theophylline. In : Current Trends in Pharmacology (Eds: A Ray, K Gulati), New Delhi, IK International, pp.443-460, 2007.
9). Gulati K, Ray A. Immunotoxicity In : Handbook of Toxicology of Chemical Warfare Agents ( ed. R Gupta ), Elsevier Publication, 595-60, 2008.
10). Ray A, Gulati K. Pharmacodynamics . In : Textbook of Pharmacology (Ed. Prof. S.D. Seth), , New Delhi, Elsevier Publication, 2009
11). Ray A, Gulati K. Pharmacokinetics . In : Textbook of Pharmacology (Ed. Prof. S.D. Seth and Vimlesh Seth), New Delhi, Elsevier Publication, 2009
 12). Gulati K, Ray A. Newer insights into the mechanisms of action of some herbal     adaptogens. In : Recent advances in Herbal Drug Research and Therapy ( Ed. A Ray, K Gulati), New Delhi, IK International, 201-218, 2009
13) Gulati K, Ray A. Stress: its impact on developmental and reproductive toxicology. In: Handbook of reproductive and developmental toxicology, (ed. R Gupta), Amsterdam, Elsevier Publication.825-834, 2010
 
 
 
In Non-Indexed journals
 
1).Lall SB, Gulati K, Trandolapril, Drug Alert. 4(2): 41-44, 1995.
2).Gulati K, Lall SB. Exposure of population to PVC fire: A focus on dioxins. Drug Alert 5:34-40, 1996.
3).Kheterpal K, Siddiqui TO. Nepeta Hindostana (roth) Haines, a cardioprotective unani drug. Hamdard Medicus 32: 35-43, 1989.
4).Gulati K, Ray A, Debnath PK, Bhattacharya SK. Immunomodulatory Indian   Medicinal Plants. J. Nat. Remed. 2 (2): 121 – 131, 2002.
 
 
Books (As Co-Editor)

1) Pharmacovigilance : An Update (Eds: Arunabha Ray and Kavita Gulati), Image Graphics, Delhi, 2004

2) Current Trends in Pharmacology (Eds: Arunabha Ray and Kavita Gulati), IK International, Delhi, 2007

3) Recent advances in herbal drug research and therapy (Eds. Arunabha Ray and Kavita Gulati, IK International, New Delhi, 2009